Health Care Reform and Health Services Research: What Once was Old is New Again, and Again

Managed care and health care reform: everything old is new again.

A 1991 New York Times article reported that the “pioneering” state of Arizona, a “late starter in Medicaid,” had provided a health system model for the nation in the Arizona Health Care Cost Containment System (AHCCCS). At that time, AHCCCS was the only Medicaid program in the United States in which nearly all beneficiaries were enrolled in managed care organizations (MCOs) that were reimbursed...

Ketamine-What Is Old Is New Again.

AMPylation: Something Old is New Again

The post-translational modification AMPylation is emerging as a significant regulatory mechanism in both prokaryotic and eukaryotic biology. This process involves the covalent addition of an adenosine monophosphate to a protein resulting in a modified protein with altered activity. Proteins capable of catalyzing AMPylation, termed AMPylators, are comparable to kinases in that they both hydrolyz...

Once again, complex care leads the way.

Schwarzschild and Synge Once Again

We complete the historical overview about the geometry of a Schwarzschild black hole at its horizon by emphasizing the contribution made by J. L. Synge in 1950 to its clarification. KEY: Schwarzschild solution; Synge; black hole; horizon